Dr. Kuan Wang is currently the Lab Chief of the Laboratory of Muscle Biology and Section Head of the Muscle Proteomics and Nanotechnology Section at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health.
Dr. Wang’s research team investigates muscle proteome, muscle physiology, mechanical biology and cell motility, including the discovery and naming of five new cytoskeletal proteins [filamin, titin, nebulin, P235 (talin) and nebulette] which are important in assembly, regulation and dysfunction of the cytomatrix and motility in cardiac, skeletal and smooth muscles and in non-muscle cells. He is directing an interdisciplinary team of biologists, chemists, engineers, and physicists to advance nanobiotechnology, including the design of nanomechanical device for single molecules and single cells, protein engineering, drug design and bio-informatics, to address the coupling of elasticity and interaction of intrinsically disordered signaling proteins, the mechanical stress sensing and transduction in cellular signaling and the molecular mechanisms of heart and skeletal muscle diseases and their treatments.
Dr. Wang received his Ph.D. degree in Molecular Biochemistry and Biophysics from Yale University and was professor of Chemistry and Biochemistry at the University of Texas at Austin from 1977 to 1997. Dr. Wang is the recipient of the Established Investigator Award of the American Heart Association and the highly selective MERIT Award of NIH that recognizes extramural scientists who have demonstrated superior competence and outstanding productivity in research endeavors. Dr. Wang was elected as an Academician of Academia Sinica in 2006. He serves as a member of the NIH Nanomedicine Roadmap Implementation Team.